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Dodge County Medical Examiner PJ Schoebel said Lemons overdosed on acetyl fentanyl, a potent opioid painkiller, and Williams died of a stroke.

The pieces that Huang and his colleagues were most interested in were biologically active molecular components known as amines and acetyl groups that adorn PNAG's sugary backbone.

HDAC8 removes chemical modifications called acetyl groups from other proteins, leading to alterations in gene expression patterns.

An autopsy determined that the woman’s death was caused by mixed drug toxicity, specifically from fentanyl and an analogue of fentanyl called acetyl fentanyl, the release said.

These modifications, which include the addition and removal of acetyl and methyl chemical groups, can dramatically alter chromosomal structure, thereby modulating the level of gene expression.